Science & Research

Assessment of Cannabidiolic Acid’s Neuroprotective Potential in a TDP-43 Transgenic Mouse Model of Amyotrophic Lateral Sclerosis

Cannabinoids originating from plants, such as Δ9-tetrahydrocannabinol (Δ9-THC), cannabinol, and formulations resembling Sativex, have demonstrated neuroprotective properties in various preclinical…

9 months ago

Peptides, NAD⁺, and MOTS-c: Evidence-Based Insights into Their Roles in Longevity as of 2025

In the domain of longevity research, peptides have garnered significant attention, yet only a subset demonstrates robust mechanistic support derived…

10 months ago

Targeting Aging Pathways with GLP-1 Analogs: From Metabolic Disorders to Healthspan Extension

During the August convening of the Aging Research and Drug Discovery conference in Copenhagen, representatives from Novo Nordisk and Eli…

10 months ago

Advancements in Antimalarial Therapy: Phase III Outcomes for a Novel Ganaplacide-Lumefantrine Combination

Recent Phase III trial data from Novartis have demonstrated the efficacy of GanLum, an innovative antimalarial regimen comprising ganaplacide and…

10 months ago

Regulatory Developments in Gene Therapy for Huntington’s Disease: Perspectives from uniQure’s Engagement with the U.S. Food and Drug Administration

uniQure N.V., a prominent entity in the gene therapy domain focused on developing innovative interventions for individuals with profound medical…

10 months ago

The Neuroprotective Potential of Panax ginseng in Neurodegenerative Diseases: Molecular Mechanisms, Therapeutic Evidence, and Translational Perspectives

Neurodegenerative disorders, encompassing Alzheimer’s disease (AD), Parkinson’s disease (PD), amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS), and Huntington’s disease (HD),…

10 months ago

FDA Approves Itvisma®: A Landmark Gene Therapy for SMA

In a pivotal advancement for rare disease treatment, the U.S. Food and Drug Administration (FDA) has approved Itvisma® (onasemnogene abeparvovec-brve),…

10 months ago

A Historic Milestone in Personalized Genetic Medicine: Israel’s First Individualized RNA Therapy for a Rare Neurodevelopmental Disorder

In a groundbreaking achievement for precision medicine in Israel — and one of the very few such cases worldwide —…

10 months ago

Extracellular Vesicles as Mediators of Systemic Toxic Injury Propagation: A Neuroscience and Molecular Biology Perspective

Extracellular vesicles (EVs), particularly exosomes and microvesicles, are a highly conserved intercellular communication system. Under severe toxic stress, EVs can…

10 months ago

Exclusive: Dr. Ariel Ionescu on the microRNA-126 Breakthrough That’s Giving New Hope to ALS

Ariel Ionescu, the scientist who co-founded Rinnerva Therapeutics and has spent years developing a truly innovative therapy for amyotrophic lateral…

10 months ago